The IGH carries out excellent basic research and aims to bring it to fruition in the field of pathology. The main research topics are genome and chromatin dynamics, developmental genetics, epigenetic control and molecular and cellular pathologies.
Three major research areas are established within the IGH:
- Genome dynamics and epigenetic control. The main aspects of this research concern DNA replication, maintenance of genome integrity, recombination and meiosis, retrotransposition and its control, chromatin and nuclear organisation, regulation of gene expression, and RNA silencing.
- Developmental genetics. This research relies heavily on model organisms such as Drosophila and transgenic mice. Topics include cell cycle and microtubule dynamics, gonadal development, RNA regulation in development, neurogenetics and memory.
- The understanding, diagnosis and treatment of human diseases. This work concerns DNA metabolism, epigenetic regulations and signalling pathways in cancer, the molecular basis of myogenesis, immunity, inflammatory diseases, AIDS, neurodegenerative diseases and cell-based therapies.
Label : Joint Research Unit (UMR)
Main supervisors: CNRS, UM
Scientific Department: Biology and Health
Graduate school: Chemical and Biological Sciences for Health