Science at UM [S03-ep21]: The antipsychotics of tomorrow
This week on A l’UM la science, we discuss a new treatment for schizophrenia with Franck Vandermoere, a researcher at the Institute of Functional Genomics. The report takes us to the Isoflux platform at Ecotron with Joana Sauze and Clément Piel. A program broadcast on Divergence-FM 93.9.
If I say "psychosis," your mind might conjure up this music and the character of Norman Bates and his famous creator Alfred Hitchcock, but very few of us are able to define what psychosis is. According to the Vidalmedical dictionary: "Psychosis is a mental illness that causes, at times, an inability to distinguish between reality and unreality. Psychoses manifest themselves in hallucinations and delusions. The psychotic person is not aware of their illness. Their language and behavior can become so disorganized that they can no longer communicate with the outside world." Within this generic term of psychosis, there are many so-called psychotic disorders such as bipolar disorder, persistent delusional disorders, and the most well-known clinical form: schizophrenia. Here too, cinema has bombarded us with the most severe forms of the illness in films such as Black Swan and Shutter Island.
In reality, schizophrenia affects 1% of the world's population. The clinical picture of the disease varies greatly from one individual to another, with a wide range of possible symptoms: delusions, hallucinations, feelings of persecution, apathy, emotional blunting, disorganization, etc.
All these symptoms make it difficult to manage and treat this disease. However, research continues to advance and new mechanisms continue to be discovered, paving the way for better treatment options.
Our guest is Franck Vandermoere, a researcher at the Institute of Functional Genomics. Together with a team from Huazhong University in Wuhan, he has just published an article in Science Advances on a new class of antipsychotic drugs targeting the MGlu2 glutamate receptor.
Read the press release:
A new mechanism of action for the antipsychotics of tomorrow
In the second part of the program, we conclude our visit to Ecotron with thisfourth and final report. Joana Sauze and Clément Piel present the Iso-Flux platform, whose mission is to analyze all gas flows, especially greenhouse gases, observable on the three experimental platforms.
At UM Science, you have the program, so let's get started!
Co-production: Divergence FM / University of Montpellier
Host: Lucie Lecherbonnier
Interview: Aline Périault / Lucie Lecherbonnier
Reporting: Aline Périault, Lucie Lecherbonnier
Editing: Lucie Lecherbonnier
Production: Alice Rollet / Tom Chevalier
Listen to the program “A l’UM la science” on Divergence FM 93.9
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