A l'UM la science [S03-ep21]: Tomorrow's antipsychotics

This week on A l'UM la science we talk about a new treatment for schizophrenia with Franck Vandermoere, researcher at the Institute of Functional Genomics. The report takes us to the Isoflux platform at the Ecotron with Joana Sauze and Clément Piel. A program broadcast on Divergence-FM 93.9.

If I say psychosis, your mind may conjure up this music, as well as the character of Norman Bates and his celebrated creator Alfred Hitchcock, but very few of us can define what psychosis is. According to the Vidal medical dictionary: " Psychosis is a mental illness that results in periods of inability to discern the real from the unreal. Psychoses are characterized by hallucinations and delusions. Psychotics are unaware of their illness. Their language and behavior can become so disorganized that they can no longer communicate with the outside world. Within the umbrella term of psychosis, we find numerous so-called psychotic disorders, such as bipolarity, persistent delusional disorders and the best-known clinical form: schizophrenia. Here too, the cinema has provided us with a wealth of examples of the most severe forms of the disease, with films such as Black Swan and Shutter Island.

In reality, schizophrenia affects 1% of the world's population. The clinical picture of the disease varies greatly from one individual to another, with a wide range of possible symptoms: delusions, hallucinations, feelings of persecution, apathy, emotional blunting, disorganization...

All these symptoms make it difficult to manage and treat this disease. Yet research continues to advance, and new mechanisms continue to be uncovered, paving the way for better treatment prospects.

Our guest is Franck Vandermoere, researcher at the Institute of Functional Genomics. With a team from Huazhong University in Wuhan, he has just published an article in Science Advances on a new class of antipsychotic targeting the MGlu2 glutamate receptor.

Joana Sauze and Clément Piel introduce us to the Iso-Flux platform, whose mission is to analyze all gas flows, especially greenhouse gases, observable on the 3 experimental platforms.

At UM la science you've got the program, here we go!

Coproduction : Divergence FM / Université de Montpellier
Animation : Lucie Lecherbonnier
Interview : Aline Périault / Lucie Lecherbonnier
Reporting : Aline Périault, Lucie Lecherbonnier
Editing : Lucie Lecherbonnier
Production : Alice Rollet / Tom Chevalier

Listen to the program "A l'UM la science" on Divergence FM 93.9