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The LabUM EpiGenMed research program builds on the international recognition of Montpellier’s research in epigenetics, (epi)genomics, and gene expression, which it aims to consolidate and expand into other fields. EpiGenMed fosters collaborations between basic research, medical research, and education in Montpellier.  It is part of the University of Montpellier’s I-SITE program of excellence and is affiliated with the Biology-Health cluster, specifically the Genetics-Epigenetics research track. The scientific scope of LabUM EpiGenMed covers epigenetics, epigenomics, and gene expression, with the goal of studying the mechanisms underlying cellular development, immune defense, and metabolism, as well as their links to diseases. Research in these fields is evolving rapidly, and a key focus is therefore the development of new technologies and facilitating their transfer to industrial partners in the healthcare sector. Initiatives PhD Training Networks LabUM EpiGenMed’s collaborative doctoral program funds networks comprising three research teams from Montpellier for the joint training of three doctoral students. Four networks have been established since 2021. Collaborative Projects LabUM EpiGenMed aims to promote collaborative projects among Montpellier-based research teams on topics related to genetics and epigenetics. The call for proposals focuses on projects that address the complexity of biological mechanisms in physiological or pathological contexts. Six projects funded with a total of 300,000 € for a duration of 24 months. Proof-of-Concept Projects “Proof-of-Concept Projects” funding supports emerging concepts or new technological approaches that are still in a preliminary stage and require further development. The projects are conducted collaboratively by two research teams. Six projects funded at €50,000 for a duration of 24 months. Events LabUM organizes and subsidizes international events in Montpellier. Prestigious Seminar Series: 3–4 seminars per year featuring renowned international speakers. Call for Proposals for Financial Support for International Conferences: 12 events organized in 2023 or 2024 received funding ranging from €3,000 to €10,000. Workshop in Epigenetics: Annual workshop for master’s students (M2) plus seminars.

BioCampus Montpellier (BCM) Biocommunication in Cardiometabolic Diseases (BC2M) BioCentre Lunaret Montpellier (BIOLuM) Stem Cells, Cellular Plasticity, Tissue Regeneration, and Immunotherapy for Inflammatory Diseases (IRMB) Center for the Study of Infectious Diseases and Anti-Infective Pharmacology (CEMIPAI) Center for Structural Biology (CBS) Montpellier Center for Cell Research (CRBM) Embryonic Development, Fertility, and Environment (DEFE) Muscle Dynamics and Metabolism (DMEM) EuroMov Digital Health in Motion (EuroMov DHM) Génopolys Initial Management and Prevention of Acute Organ Failures in Critically Ill Patients (IMAGINE) Institute of Human Genetics (IGH) Montpellier Institute of Molecular Genetics (IGMM) Institute of Functional Genomics (IGF) Montpellier Institute of Neurosciences (INM) Montpellier Research Institute (IRCM) Montpellier Institute for Research (IRIM) Desbrest Institute of Epidemiology and Public Health (IDESP) Bioengineering and Nanosciences Laboratory (LBN) Laboratory of Pathogens and Host Immunity (LPHI) Molecular Mechanisms in Neurodegenerative Dementias (MMDN) Pathogenesis and Control of Chronic and Emerging Infections (PCCEI) Physiology and Experimental Medicine of the Heart and Muscles (PhyMedExp) Translational Research on HIV and Endemic and Emerging Infectious Diseases (TransVIHMI) Bacterial Virulence and Chronic Infections (VBIC) Partnership-Based Research Structures: Host-Vector-Parasite-Environment Interactions in Neglected Tropical Diseases Caused by Trypanosomatids (INTERTRYP) Modeling and Engineering of Complex Biological Systems for Diagnosis (Sys2Diag)

Doctoral Schools Affiliated with the Biology and Health Cluster (CBS2) — Chemical and Biological Sciences for Health The CBS2 doctoral school trains doctoral candidates in all fields of biology and health, from medicinal chemistry to clinical studies, and from genetics to behavior. Supported by the laboratories of the Biology-Health Cluster and the Doctoral College of the University of Montpellier, it offers training focused on and driven by research and prepares future PhD graduates for careers in both academia and the private sector. CBS2 Doctoral School Website SMH - Human Movement Sciences Doctoral School 463 “Human Movement Sciences” brings together the research capabilities of the major university clusters in the Greater Southeast (Aix-Marseille, Montpellier, and Nice) in the field of human movement and its neurological, physiological, mechanical, behavioral, cognitive, and societal determinants. ED SMH website Biology and Health Programs University of Montpellier Program Offerings Website

FHU T.I.E. “Triangular Analysis of Interactions Between Host, Infectious Agent, and Environment” Dr. A. MAKINSON (UM Montpellier) and Prof. E. TUAILLON (UM Montpellier) The University Hospital Federation (FHU) TIE [taɪ]—whose acronym refers to its overarching objective of modeling human–microorganism interactions, from emergence to long-term complications, through a triangulation between the host, infectious agents, and the environment—brings together stakeholders in the Montpellier-Nîmes region involved in research and care related to infectious diseases and related fields (microbiology, immunology, public health). Although the resources available to the FHUs are modest, these federations—which have existed in France since 2012—aim to stimulate translational research, improve the quality of care, and foster collaboration between university hospitals, research laboratories, and the private sector. Newsletter April 2024 NewsletterDownload Conferences FHU TIE & G2i Annual Conference: Microbiota: Between Yin and Yang - Wednesday, June 26, 2024 - Agropolis Amphitheater, 1000 Avenue Agropolis, 34394 MontpellierFHU TIE Website Download the program: FHU TIE G2i Symposium Download Registration FHU Regenhab 2.0 “Regenerative Medicine, Motion Modeling, and Rehabilitation” Prof. C. JORGENSEN (IRMB, U1183) and Dr. A. LACAMPAGNE (Phymedex, U1046)FHU Regenhab 2.0 website FHU Evocan-2 “Immunotherapies in Cancer” Prof. G. CARTRON (UM Montpellier) and Dr. N. BONNEFOY (ICM, U1194) FHU Evocan website

CeAND The Center of Excellence on Autism and Neurodevelopmental Disorders (CeAND) is an interdisciplinary research network aimed at fostering collaboration among researchers, practitioners in the field, as well as families and individuals affected by these conditions, in order to promote and disseminate best practices in care and education. CeAND website CoEN The overall objective of the Center of Excellence in Neurodegenerative Diseases (CoEN) in Montpellier is to build a collaborative research program in the field of neurodegeneration that transcends national borders, with a focus on critical mass and excellence. CoEN website

What sets the UMI TransVIHMI apart is its multidisciplinary approach, whose primary initial objective is to study the specific characteristics of HIV and associated diseases—particularly tuberculosis—from epidemiological, virological, bacteriological, parasitological, clinical, and social perspectives. The unit has expanded its focus to include non-HIV infections—no longer limited to the context of HIV co-infection—as well as neglected and emerging tropical diseases. Consequently, more recent work has led to the development of a new research-intervention focus as part of the response to epidemics (Ebola). Designation: International Joint Unit (UMI) Primary Sponsors:UM, Inserm, IRD Research Cluster: Biology and Health Doctoral Schools: Chemical and Biological Sciences for Health HAL Portal: unit publications Website