ExposUM Doctoral Nexus: 2025 Thesis Topics – Applications Closed
What is the ExposUM Doctoral Nexus program?
The Doctoral Nexus programs offered by the ExposUM Institute are networks of 3 to 4 doctoral researchers from different disciplines who are affiliated with at least two different research units.

Compared to a traditional dissertation, participating in a Doctoral Nexus will help develop the ability to work in a team and design projects in a transdisciplinary manner, while deepening one’s own field of expertise.
A specialized educational program will be offered, and the participating doctoral students will also have the opportunity to organize a seminar within the Nexus network.
Ph.D. programs are funded for four years from the outset, covering the doctoral student’s salary as well as a budget for research support.
On the following page, you will find the ExposUM Doctoral Nexus projects that were selected through the 2025 Doctoral Nexus Call for Proposals.
Applications are now closed
Applications for the thesis topics listed below are now closed. These are provided for illustrative purposes only.
2025 Thesis Topics: Applications are now closed
Nexus AMYLOPATH :“Exploring Microbe-Induced Amyloidoses through an Interdisciplinary Approach”
- Topic 1 “Development and application of computational approaches to study the mechanisms of microbe-induced amyloidogenesis.”
AMYLOPATH Topic 1 Kajava EN - Topic 2 “Co-condensation of yeast prion-like proteins”
AMYLOPATH Topic 2 Caudron EN - Topic 3 “Gut Microbiota and Amyloidosis in Alzheimer’s Disease”
AMYLOPATH Topic 3 Claeysen FR
AMYLOPATH Topic 3 Claeysen EN
Nexus CLIMAnX “Experienced or Anticipated Climate Change and Mental Health: From Anxiety to Adaptive Well-Being”
- Topic 1 “Impact of Environmental Disasters on the Use of Psychotropic Drugs in France”
CLIMAnX Topic 1 Artero & Parmentier FR
CLIMAnX Topic 1 Artero & Parmentier EN - Topic 2 “Preclinical study of the influence of ‘heatwave’ thermal stress on brain activity and on cognitive and social performance”
CLIMAnX Topic 2 Becamel & Givalois FR
CLIMAnX Topic 2 Becamel & Givalois EN - Topic 3 “Climate Anxiety, Mental Health, and Student Success: Factors, Consequences, and Educational Interventions”
CLIMAnX Topic 3 Bächtold & Brun FR - Topic 4: “Patterns of Exposure to Climate Risks, Eco-Anxiety, and Social Cohesion”
CLIMAnX Topic 4 Rey-Valette & Bazart FR
CLIMAnX Topic 4 Rey-Valette & Bazart EN
Nexus EXPO-PMT “An Integrated Approach to Persistent, Mobile, and Toxic Pollutants in Water Resources: Assessing Their Contribution to the EXPOsome and Recommending Adaptation Solutions”
- Topic 1 “The Contribution of PMTs to the Aquatic Exposome: Assessment and Treatment of Water Resources Intended for Human Consumption”
EXPO-PMT Topic 1 Brosillion, Gomez EN - Topic 2: “Modeling the Spatiotemporal Toxicological Impacts of PMTs in the Drinking Water Supply Chain”
EXPO-PMT Topic 2 Servien, Patureau EN - Topic 3 “Exploring Strategies for Adapting Drinking Water Services to Resource Degradation Caused by Emerging Micropollutants: Development of a Diagnostic and Decision-Support Method”
EXPO-PMT Topic 3 Guérin-Schneider FR
Nexus INTEGRAAL “Interoception, Exposome, Gut Microbiota, Rheumatoid Arthritis, Artificial Intelligence & Ontological Linking”
- Topic 1
FULL Text Topic 1 Olié FR - Topic 2 “An Integrative Understanding of the Link Between the Environment, the Microbiome, Self-Perception, and Rheumatoid Arthritis”
FULL TEXT Topic 2 Immediato-Daien & Bourinet FR - Topic 3 “Hybrid Model for Predicting Rheumatoid Arthritis (RA) Based on Machine Learning Enriched by a Dynamic Ontology of the Disease and the Exposome”
FULL TEXT Topic 3 Bringay & Abrouk FR
Nexus LEPTONEX “Leptospires and Exposure Nexus: Interactions Between Humans, Dogs, Nutrias, and the Environment”
- Topic 1 “Geographic, Social, and Cultural Determinants of Risks Associated with Interactions Between Humans and Nutrias”
LEPTONEX Topic 1 Caillon FR
- Topic 2 “Multiscale Modeling of the Spatial Dynamics of the Nutria”
LEPTONEX Topic 2 Gimenez FR
LEPTONEX Topic 2 Gimenez EN - Topic 3 “Characterization of the diversity and circulation dynamics of leptospires in nutria populations using a combination of epidemiological and landscape genetics approaches”
LEPTONEX Topic 3 Charbonnel FR
LEPTONEX Topic 3 Charbonnel EN