Terratis is making waves in the fight against the tiger mosquito

Following an evaluation and proposal by the University Innovation Hub led by the University of Montpellier, BPI France announced during the “4th Anniversary of the DeepTech Plan” on March 28 the first BFT Lab shortlist, featuring Terratis, a future Montpellier-based startup. Implemented by the French government, this grant is intended for pre-launch projects within the PUI that are undergoing technical pre-maturation or maturation, to help them accelerate their market entry. For Terratis, the BFT Lab will facilitate the implementation and industrialization in France of the Sterile Insect Technique (SIT). Developed in Réunion by the French National Research Institute for Sustainable Development (IRD), this method for controlling the tiger mosquito can also be applied to agricultural pests of concern to the Occitanie region.

A mosquito bite can be more or less unpleasant—or even dangerous—depending on the species and the person. Shutterstock

Behind the scenes of a preliminary selection

Reducing the mosquito population… by releasing mosquitoes. That is the principle behind TIS, which aims to combat Aedes albopictus in particular by releasing previously sterilized males. This technology is generating interest nationwide with the initial selection of the future Montpellier-based startup Terratis to receive this grant, which complements the technology maturation initiative led and funded by SATT AxLR to the tune of €850,000.  BFT Lab supports project leaders mentored by member institutions of the Montpellier PUI in collaboration with the University of Montpellier, the world’s third-ranked university in the field of ecology.

This national first serves as a prime example of the UM’s ability to bring together all innovation stakeholders within the Montpellier University Research Institute (PUI) to support and guide our laboratories in commercializing their research. Terratis, co-founded and led by Clelia Oliva, has thus been able to benefit from the full range of expertise developed and expanded within the PUI, which is now complemented by this BFT Lab.

This outstanding recognition from BPI France strongly motivates the University of Montpellier to continue this work and its commitment to presenting the government with a vision of the regional innovation ecosystem developed in Montpellier.

“Montpellier is a major research hub from which a large number of innovative startups are emerging. It’s a real springboard for a young company like ours, which is part of the Med Vallée ecosystem. “We benefit from technology transfer through the IRD and our strong ties with the teams based in Montpellier, which are key to the solid implementation of the TIS and the company’s success,” says Clelia Oliva, co-founder and director of Terratis.

TIS: Serving Communities and Large Private Properties

Terratis is working on the industrialization of the Sterile Insect Technique (SIT) for its future deployment in France. This technique makes it possible to gradually reduce tiger mosquito populations in a given area by interfering with their reproductive cycle. Since male mosquitoes do not bite, the process simply involves releasing sterilized males so that they mate with wild females, thereby preventing their reproduction.

“Since the insects do all the work naturally and without designated treatment zones, this approach benefits all citizens. Its effectiveness has already been proven in several regions. On Réunion Island, the proof-of-concept study conducted by the IRD in 2022 reduced fertility by 60% at the neighborhood level. “We are working with local stakeholders to use this ecological and more targeted solution as a complement to traditional tools for controlling the tiger mosquito, once our large-scale breeding farm project becomes operational by 2028,” adds Clelia Oliva.

For local governments, large private spaces such as campgrounds or recreational parks, or even airports, the positive impacts will be significant in terms of reducing costs associated with noise pollution and health risks, as well as improving quality of life.

“This ambitious business venture, the only one of its kind in France, has come to fruition thanks to the support and guidance of Montpellier’s innovation and research ecosystem, particularly the University of Montpellier and its INITIUM incubator, the Montpellier BIC, the SATT AxLR, IRD, and INRAE, as well as the Occitanie Region,” explains Clelia Oliva

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About the University of Montpellier: With its 17 faculties, schools, and institutes and 74 research centers, the University of Montpellier brings together a vast community of knowledge spanning science, technology, physical education and sports, medicine, pharmacy, law, political science, economics, and business administration.  With over 52,000 students and 4,800 staff members, the University of Montpellier is now one of France’s largest universities. UM is internationally recognized for the excellence of its education and research (ranked in the top 200 in the Shanghai General Ranking and in the top 3 in ecology in its subject-specific ranking). The University of Montpellier, which is also ranked among the most innovative European universities (Reuters ranking), has been home to a “University Innovation Hub” (PUI) since 2022. As part of the collective momentum driven by the I-SITE excellence program, it brings together 10 research organizations, 3 healthcare institutions, and 2 schools, and involves key players in the innovation ecosystem such as the SATT AxLR, the Montpellier Metropolitan Area Business Incubator (BIC), the Occitanie Region Economic Development Agency, and BPI France. From training to business creation, the Montpellier PUI promotes early detection and support, particularly through the “PEPITE DeepTech” initiative, and fosters the synergy of innovation mechanisms at the local level. Since 2020, startups leveraging the research work of the Montpellier PUI’s partners have raised over €300 million.

About Terratis: This young research-based startup from Montpellier, currently being founded by Clelia Oliva and Allan Debelle, is committed to responsible pest management. Terratis is working on the industrialization and deployment of STT (Sterile Insect Technique). The establishment of a pilot production line and a market validation phase is expected to create 7 jobs in 2024, with more than 15 additional jobs by 2028 for the operational launch of the mass breeding farm. Studies regarding the breeding farm project and its location will begin in 2024 in collaboration with local stakeholders.

About the IRD : The French National Research Institute for Sustainable Development (IRD) is a multidisciplinary French public research organization that, for nearly 80 years, has been engaged in equitable partnerships with countries in the Global South and France’s overseas territories. As a key player in the international development agenda, its priorities are aligned with the implementation of the Sustainable Development Goals (SDGs). Together, the Institute’s scientists and partners propose concrete solutions to address the global challenges facing societies and the planet. This win-win relationship makes science and innovation major drivers of development.

About SATT AxLR: SATT AxLR is a technology transfer acceleration company specializing in the development and commercialization of innovative projects stemming from public research. It works with most of the public research laboratories located in Occitanie, one of the most dynamic regions in France and Europe, with nearly 200 laboratories and nearly 11,000 researchers and research staff. Since its creation, SATT AxLR has funded 192 innovation programs, invested €67 million, signed 173 technology transfer agreements with companies, and supported 119 startups.