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Label: Joint Research Unit Research UMR)Main sponsoring organizations: UM, Inserm, UPS ToulouseResearch cluster: Biology and HealthDoctoral school: Chemical and Biological Sciences for HealthHAL portal: publications from the unit WEBSITE

The Montpellier Center for Cell Biology Research is a laboratory affiliated with the CNRS and the University of Montpellier. The CRBM is internationally recognized in the field of molecular and cellular biology. Its research aims to understand the mechanisms controlling cell division, morphology, and adhesion under normal and pathological conditions, with a particular focus on cytoskeletal dynamics, post-translational modifications, and the intracellular signaling mechanisms regulating these cellular activities. Label: Joint Research Unit Research UMR)Main sponsoring bodies: CNRS, UMPResearch cluster: Biology and HealthDoctoral school: Chemical and Biological Sciences for HealthHAL portal: publications of the unit WEBSITE

https://youtu.be/U-4QGKRe4wY Le CEMIPAI est un laboratoire de services du CNRS et de l’université de Montpellier, ouvert aux équipes académiques et aux entreprises. Il s’organise autour de l’un des plus grands laboratoires de sécurité microbiologie de niveau L3 de France, permettant de travailler en atmosphère contrôlée sur les prélèvements biologiques infectieux et les agents biologiques de classe 3, comme le virus de l’immunodéficience humaine (VIH), les virus des hépatites ou les virus transmis par les moustiques (Chikungunya, Dengue, Zika), les bactéries pathogènes et les prions. Le CEMIPAI accueille les équipes, forme les chercheurs à la manipulation des agents infectieux et développe des tests en cultures cellulaires permettant de rechercher des molécules d’intérêt thérapeutique développées par les chercheurs du privé et du public. Des équipements de pointe en microscopie super résolue permet d’observer cellules infectées, virus et bactéries à des échelles nanométriques. Label : Unité d’Appui et de Recherche (UAR)Tutelles principales : CNRS, UMPôle de recherche : Biologie SantéPortail HAL : publications de la structure SITE WEB

The CBS’s overarching goal is to conduct cutting-edge research in structural biology, biophysics, and bioengineering to identify and characterize the fundamental mechanisms of life and their regulation across different temporal and spatial scales (from individual molecules to living tissues and organisms) using integrative approaches. We are particularly interested in understanding the molecular and physical determinants of these processes using state-of-the-art methodologies. We believe that achieving these objectives requires studying the structure and dynamics of supramolecular assemblies at different scales, as well as a detailed understanding of their assembly and regulatory mechanisms. Furthermore, our ambition is to study these processes in more integrated contexts such as living cells or model organisms. Where possible, we also apply this knowledge to design new therapeutic strategies for human health and disease. Label: Joint Research Unit Research UMR)Main sponsoring bodies: CNRS, UM, InsermResearch cluster: Biology and HealthDoctoral schools: Information, Structures, Systems; Chemical and Biological Sciences for HealthHAL portal: publications of the unit WEBSITE

BioCampus Montpellier is a research consortium comprising 12 high-level technology platforms. These platforms serve a scientific community of 2,000 Professors most Professors teams are affiliated with the AGRO, CeMEB, and EpiGenMed Labex programs. The UMS offers its services to researchers within these units as well as to industry partners with the aim of establishing new collaborative networks. Its platforms offer “open access” services, scientific and technical expertise, training in the form of technology workshops, and more. Themes: Bioinformatics, Structural Biology, Breeding and Functional Exploration, Histology, Imaging, Small Animal Imaging, Molecular Combing, Recombinant Proteins, Genomics, Pharmacology, Proteomics, Vectorology. Label: Support and Research Unit Research UAR)Main sponsoring bodies: CNRS, UM, InsermResearch cluster: Biology and HealthHAL portal: the unit’s publications WEBSITE

Our research group focuses on the bio-communication between the cardiovascular/renal axis and metabolic tissues within the complex pathophysiological context of metabolic syndrome. Our work aims to better characterize the pathophysiological mechanisms involved in the damage to various target tissues (cardiovascular and metabolic) during metabolic dysfunction, as well as the bio-communication pathways between these tissues. Through this integrative approach to chronic diseases, we hope to develop new therapeutic strategies aimed at preventing damage to cardiovascular and metabolic tissues, thereby reducing cardiovascular risk and metabolic dysfunction. Label: UR_UM101Primary affiliation: UMResearch cluster: Biology and HealthDoctoral school: Chemical and Biological Sciences for HealthHAL portal: publications of the unit WEBSITE

The mission of the Sciences for Oenology unit is to conduct fundamental research in plant biology, microbiology, biochemistry, chemistry, and physical chemistry, with a primary focus on the viticulture and winemaking sector. Researchers in the unit concentrate primarily on topics related to: The integrative physiology of oenological yeasts and the control of alcoholic fermentation; Phenolic compounds (biosynthesis, reactivity, physicochemical interactions, properties, and utilization). Label: Joint Research Unit Research UMR)Main sponsoring bodies: UM, INRAE, Institut AgroResearch cluster: Agriculture-Environment-Biodiversity Cluster (AEB)Doctoral school: Biodiversity, Agriculture, Food, Environment, Earth, WaterHAL portal: publications of the unit WEBSITE

The QualiSud unit conducts scientific research aimed at analyzing, understanding, and optimizing the process of building food quality throughout the processing chain. Sensory quality, health effects, and health risks are given particular attention. The research activities of the QualiSud UMR are structured around five scientific areas: process bioguidance based on sensory qualities and food safety; control of post-harvest quality in fresh fruits and vegetables; strategies for the prevention and control of mycotoxins throughout the food supply chains; study of mass transfer and reaction kinetics during the fermentation of solid foods; multicriteria analysis and design for decision support in the agri-food sector. Label: Joint Research Unit Research UMR)Main sponsoring organizations: UM, CIRAD, IRD, Institut Agro, U RÉUNION, UAPVResearch cluster: Agriculture, Environment, Biodiversity – AEBDoctoral school: Biodiversity, Agriculture, Food, Environment, Earth, WaterHAL portal: publications of the unit WEBSITE

Numerous interactions occur between the various micro- and macro-organisms in agroecosystems and plants. These interactions, which determine plant health, growth, and productivity, are often poorly understood. The PHIM Joint Research Unit (UMR) generates knowledge and solutions to improve plant health and increase plant productivity and quality. PHIM uses approaches from molecular biology and genetics, population genetics and genomics, epidemiology, and population dynamics and modeling to study these interactions at scales ranging from the cell to the crop plot. Label: Joint Research Unit Research UMR)Primary sponsors: CIRAD, INRAE, IRD, Institut AgroSecondary sponsor: UMPResearch cluster: Agriculture, Environment, Biodiversity – AEBDoctoral school: Biodiversity, Agriculture, Food, Environment, Earth, WaterHAL portal: publications of the unit WEBSITE

OREME focuses its scientific activities on natural hazards and the impact of global and anthropogenic changes on the Mediterranean region, drawing on the scientific and technical expertise of its partners in geosciences, hydrosciences, biodiversity sciences, and ecology. Its mission is: to support the implementation or development of systematic observation in space and environmental sciences; to support the creation of open, shared, and internationally referenced environmental databases; to encourage the pooling of analytical resources (observation, experimentation, modeling) and expertise; to serve as the local hub for national observation networks and position itself as a key player in Mediterranean-focused environmental initiatives. OREME therefore focuses on three fundamental questions: the origin and assessment of natural and anthropogenic hazards and disturbances; the recording of recent and current global changes, their links to anthropogenic factors, and in particular changes in the use of Mediterranean environments; the response of the systems and mechanisms involved. Drawing on the educational resources of the University of Montpellier for its educational mission, OREME focuses on its ability to mobilize extensive and sustainable observation resources and recognized scientific and technical expertise across a wide range of aspects of the Mediterranean’s physical, chemical, and biological environment: geodesy, gravimetry, and deformation of the Earth and its surface; hydrogeological, hydrological, and geophysical monitoring of aquifers, particularly karstic ones; monitoring of the Languedoc coastline, the interface between the watershed and the marine environment, and the shoreline; pollution and biological adaptability downstream of former mining sites; measurement of fluxes (CO2, water, gases) and ecosystem functioning; phenology of terrestrial flora and fauna; dynamics of animal and plant communities; population dynamics of model organisms. It also houses three major regional technical platforms: GLADYS for integrated coastal studies, AETE for water pollution analysis, and the Sète Marine Station (SMEL). OREME’s continuous observation enables the collection and dissemination of data on environmental change at the national and international levels, as well as the conduct of fundamental and applied research. Label: Support and Research Unit Research UAR)Main sponsoring bodies: CNRS, UM, INRAE, IRDResearch cluster: Agriculture, Environment, Biodiversity – AEBHAL portal: publications of the organization WEBSITE

MIVEGEC conducts integrative research on the molecular and ecological mechanisms that sustain and/or amplify the persistence and transmission of pathogens. The research topics cover a broad spectrum, combining fundamental aspects of biology, genetics, ecology, and the evolution of parasitic and symbiotic systems with more applied objectives aimed at developing tools and strategies capable of reducing the spread of diseases in humans and animals, particularly through integrated ecosystem management and the control of insect vectors. This places MIVEGEC at the interface between Public Health and the Environment, Biology and Medicine, Ecology and Evolution. This research applies to various infectious models (parasites, viruses, bacteria, etc.) as well as to non-strictly infectious models such as cancer. Label: Joint Research Unit Research (UMR)Primary Affiliations: CNRS, UM, IRDSecondary Affiliation: INRAEResearch Cluster: Agriculture, Environment, Biodiversity – AEBDoctoral Schools: Chemical and Biological Sciences for Health; Biodiversity, Agriculture, Food, Environment, Earth, WaterHAL Portal: publications of the unit WEBSITE

https://youtu.be/RvoapzUL1wc L’objectif général de l’UMR concerne l’étude de la biodiversité marine des écosystèmes lagunaires, côtiers et hauturiers à différents niveaux d’intégration (moléculaire, individu, population et communauté), et des usages de cette biodiversité par l’Homme. S’appuyant sur des outils variés d’observation, d’expérimentation, d’analyse et de modélisation, l’unité répond plus spécifiquement aux objectifs suivants : décrire la biodiversité marine, comprendre sa dynamique et le fonctionnement des écosystèmes marins ; analyser l’impact des pressions anthropiques sur ces écosystèmes et développer des scenarii de réponses au changement global ; concilier exploitation (en particulier pêche et aquaculture) et conservation et répondre aux attentes sociétales (expertise, innovation, remédiation). Label : Unité Mixte de Recherche (UMR)Tutelles principales : UM, IRD, CNRS, IFREMERPôle de recherche : Agriculture, Environnement, Biodiversité – AEBÉcole doctorale : Biodiversité, Agriculture, Alimentation, Environnement, Terre, EauPortail HAL : publications de la structure SITE WEB

Research at ISEM focuses on the origins and dynamics of biodiversity, as well as the processes and mechanisms driving its evolution. Researchers in this unit examine both current and past biodiversity, study a wide range of organisms and environments, and combine fieldwork, experimental, and theoretical approaches. This research integrates: fundamental questions in evolutionary biology (adaptation, constraints, speciation, etc.) to understand the mechanisms underlying biodiversity, its structure, and its functioning; the acceleration of data generation methods and the ability to grasp the various structural and functional dimensions of life (from the gene to the ecosystem), leading to a comprehensive understanding of the mechanisms underlying biodiversity; scientific and societal inquiries into the responses of biodiversity (organisms and/or communities) to global and anthropogenic changes. Label: Joint Research Unit Research UMR)Primary Affiliations: CNRS, UM, IRD Secondary Affiliations: CIRAD, EPHE Research Cluster: Agriculture, Environment, Biodiversity – AEB Doctoral Schools: Information, Structures, Systems; Chemical and Biological Sciences for Health; Biodiversity, Agriculture, Food, Environment, Earth, Water HAL Portal: publications of the unit WEBSITE

The IPSIM Joint Research Unit seeks to elucidate the physiological mechanisms governing plant water and mineral nutrition and their responses to abiotic stresses and climate change (water stress, salinity stress, mineral deficiencies, metal toxicity, CO₂, high temperatures). The research programs focus on water and mineral ion transport in plants, mineral accumulation in seeds, the mechanisms of perception and signaling of environmental stresses, and developmental responses to these stresses (particularly in the root system). The approach is that of integrative biology, which combines methods from molecular and cellular biology, biochemistry and biophysics, functional genomics, and genetics, using model plants (Arabidopsis thaliana) or crops of agronomic interest (maize, rice, wheat, grapevine, lupin). Label: Joint Research Unit Research UMR)Primary Affiliations: CNRS, UM, INRASecondary Affiliation: Institut AgroResearch Cluster: Agriculture, Environment, Biodiversity – AEBDoctoral School: Biodiversity, Agriculture, Food, Environment, Earth, WaterHAL Portal: publications of the unit WEBSITE

The “Host-Pathogen-Environment Interactions” (IHPE) laboratory is a Joint Research Unit Research UMR 5244) jointly administered by the University of Perpignan Via Domitia (UPVD), the National Center for Research (CNRS / INEE Institute), the French Research Institute Research Exploitation of the Sea (Ifremer), and the University of Montpellier (UM). The laboratory’s staff are based on the campuses of the University of Perpignan Via Domitia and the University of Montpellier (Faculty of Sciences). The laboratory is a member of the Labex “Mediterranean Center for Environment and Biodiversity” (CeMEB) and “Toward a Unified Theory of Biotic Interactions: Role of Environmental Perturbations” (TULIP), and serves as a collaborating center for the WHO due to its expertise in host-schistosome interactions (FRA-69). Our UMR develops integrative approaches to interacting biological systems involving various species of invertebrates: invertebrates of medical or veterinary interest (gastropod mollusks), aquaculture (bivalve mollusks), or ecological interest (coral). Label: Joint Research Unit Research UMR)Primary affiliations: CNRS, IFREMER, UPVDSecondary affiliation: UMResearch cluster: Agriculture, Environment, Biodiversity – AEBDoctoral school: Biodiversity, Agriculture, Food, Environment, Earth, WaterHAL portal: publications of the unit WEBSITE

UMR IATE develops a multidisciplinary scientific approach to the characterization, processing, and utilization of renewable agro-resources from the agricultural, forestry, and agri-food sectors. The UMR focuses in particular on the structure and functionality of biopolymers and biomolecules. Its multidisciplinary expertise lies at the intersection of: biochemistry; physical chemistry; process engineering; biotechnology; chemistry; physics; and numerical and computational modeling. Research addresses the complexity of agricultural resources using high-performance analytical methods and the design of innovative technological pathways for processing in the fields of agri-food, bio-based materials, biocatalysis, and bioenergy. Label: Joint Research Unit Research UMR)Main sponsoring bodies: UM, INRAE, Institut AgroResearch cluster: Agriculture, Environment, Biodiversity – AEBEDoctoral schools: Information, Structures, Systems; Biodiversity, Agriculture, Food, Environment, Earth, WaterHAL portal: publications of the unit WEBSITE