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The EuroMov Digital Health in Motion research unit aims to promote cross-fertilization between artificial intelligence, movement sciences, and health in order to understand human behavioral plasticity, improve sensorimotor performance, and develop new therapeutic approaches. It also seeks to find a scientific metaphor that will inspire new digital approaches: machine learning or adaptive control of complex systems, human/machine interaction, and context-sensitive software systems. https://youtu.be/xaUOKgoUwYI?list=PL6WmOx60MnJe_iazdaxlxc1zC3Mx1K3Z0 This line of research on "Digital Health in Motion" ultimately aims to better understand the etiology of human movement, considered as the level of integration of biological and cognitive phenomena, during our constant informational exchanges with the environment. The research unit is organized into three scientific themes and two cross-cutting areas: Perception In Action & Synchronization (PIAS) theme: discovering the laws governing human perception in moving agents (perception in action) and human-environment synchronization in general. Monitoring and Improving Behaviors (MIB) theme: providing users with advice on how to improve their behaviors in order to achieve better health, quality of life, or athletic performance, with a particular focus on software engineering. The Learning and Complexity (LAC) theme focuses on the study of human learning and complexity through movement signatures in health, clinical data, and neural activity indicators, particularly by developing interpretable models. Cross-disciplinary Semantics and Taxonomy of Movement (SemTaxM): identifying taxonomic classifications of movement and defining a theory of movement-based semantics and semantic models anchored in specific contexts. The Factory cross-disciplinary focus aims to improve the reproducibility of results and accelerate translational research and technology transfer by providing standardized and documented approaches with an open data dissemination strategy. Label: UR_UM102 Main supervisory bodies: UM, IMT Mines Ales Research cluster: Biology and Health Doctoral schools: Information, Structures, Systems; Human Movement Sciences HAL portal: publications by the structure WEBSITE

The DMEM laboratory is a joint research unit of INRA and the University of Montpellier. We are interested in understanding the tissue, cellular, and molecular mechanisms that enable skeletal muscles to develop properly and adapt to their environment. Our hypothesis is that abnormalities in the adaptation of muscle tissue to environmental changes (diet, level of physical activity) can modulate the body's homeostasis and, more broadly, its state of health. The DMEM is therefore a fundamental research unit whose goal is to advance our knowledge of the functioning and physiology of skeletal muscles. We are also open to possible applications of our research, as evidenced by our partnership with private companies interested in our results. Label: Joint Research Unit Research UMR) Main supervisory bodies: UM, INRA Research cluster: Biology and Health Doctoral schools: Human Movement Sciences; Chemical and Biological Sciences for Health HAL portal: publications by the unit WEBSITE

Label: Joint Research Unit Research UMR) Main supervisory bodies: UM, Inserm, UPS Toulouse Research cluster: Biology and Health Doctoral school: Chemical and Biological Sciences for Health HAL portal: publications by the organization WEBSITE

The Montpellier Cell Biology Research Center is a laboratory of the CNRS and the University of Montpellier. The CRBM is internationally recognized in the field of molecular and cellular biology. Its research activity aims to understand the mechanisms controlling cell division, morphology, and adhesion under normal and pathological conditions, with a particular focus on cytoskeletal dynamics, post-translational modifications, and intracellular signaling mechanisms regulating these cellular activities. Label: Joint Research Unit Research UMR) Main supervisory bodies: CNRS, UMP Research pole: Biology and Health Doctoral school: Chemical and Biological Sciences for Health HAL portal: publications by the structure WEBSITE

https://youtu.be/U-4QGKRe4wY Le CEMIPAI est un laboratoire de services du CNRS et de l’université de Montpellier, ouvert aux équipes académiques et aux entreprises. Il s’organise autour de l’un des plus grands laboratoires de sécurité microbiologie de niveau L3 de France, permettant de travailler en atmosphère contrôlée sur les prélèvements biologiques infectieux et les agents biologiques de classe 3, comme le virus de l’immunodéficience humaine (VIH), les virus des hépatites ou les virus transmis par les moustiques (Chikungunya, Dengue, Zika), les bactéries pathogènes et les prions. Le CEMIPAI accueille les équipes, forme les chercheurs à la manipulation des agents infectieux et développe des tests en cultures cellulaires permettant de rechercher des molécules d’intérêt thérapeutique développées par les chercheurs du privé et du public. Des équipements de pointe en microscopie super résolue permet d’observer cellules infectées, virus et bactéries à des échelles nanométriques. Label : Unité d’Appui et de Recherche (UAR)Tutelles principales : CNRS, UMPôle de recherche : Biologie SantéPortail HAL : publications de la structure SITE WEB

The overall objective of CBS is to conduct cutting-edge research in structural biology, biophysics, and bioengineering to identify and characterize the fundamental mechanisms of life and their regulation, at different scales of time and space (from single molecules to living tissues and organisms) and using integrative approaches. We are particularly interested in understanding the molecular and physical determinants of these processes using state-of-the-art methodologies. We believe that the answer to these objectives involves studying the structure and dynamics of supramolecular assemblies at different scales, as well as a detailed understanding of their assembly and regulatory mechanisms. In addition, our ambition is to study these processes in more integrated contexts such as living cells or model organisms. Where possible, we also exploit this knowledge to design new therapeutic strategies for human health and disease. Label: Joint Research Unit Research UMR) Main supervisory bodies: CNRS, UM, Inserm Research cluster: Biology and Health Doctoral schools: Information, Structures, Systems; Chemical and Biological Sciences for Health HAL portal: publications by the organization WEBSITE

BioCampus Montpellier is a federative research structure that brings together 12 high-level technology platforms. These platforms serve a scientific community of 2,000 Professors most Professors teams belong to the AGRO, CeMEB, and EpiGenMed labexes. The UMS offers its services to research units as well as industrialists with the aim of establishing new collaborative networks. Its platforms offer "open access" services, scientific and technical expertise, training in the form of technology workshops, etc. Themes: Bioinformatics, Structural Biology, Breeding and Functional Exploration, Histology, Imaging, Small Animal Imaging, Molecular Combing, Recombinant Proteins, Genomics, Pharmacology, Proteomics, Vectorology. Label: Support and Research Unit Research UAR) Main supervisory bodies: CNRS, UM, Inserm Research cluster: Biology and Health HAL portal: publications by the organization WEBSITE

Our unit's project focuses on biocommunication between the cardiovascular/renal axis and metabolic tissues in a complex pathophysiological context, namely metabolic syndrome. Our work aims to better characterize the pathophysiological mechanisms involved in damage to different target tissues (cardiovascular and metabolic) during metabolic dysfunction, as well as the biocommunication pathways between these tissues. Through this integrative approach to chronic diseases, we hope to develop new therapeutic strategies with the aim of preventing damage to cardiovascular and metabolic tissues and thus reducing cardiovascular risk and metabolic dysfunction. Label: UR_UM101 Main supervisory body: UMP Research center: Biology and Health Doctoral school: Chemical and Biological Sciences for Health HAL portal: publications by the organization WEBSITE

The mission of the Sciences for Oenology unit is to develop generic research in plant biology, microbiology, biochemistry, chemistry, and physical chemistry, with a primary focus on the wine industry. Researchers in the unit concentrate mainly on topics related to: The integrative physiology of oenological yeasts and the control of alcoholic fermentation; Phenolic compounds (biosynthesis, reactivity, physicochemical interactions, properties, valorization). Label: Joint Research Unit Research UMR) Main supervisory bodies: UM, INRAE, Institut AgroPôle de recherche: Agriculture-Environment-Biodiversity Cluster (AEB) Doctoral school: Biodiversity, Agriculture, Food, Environment, Earth, Water HAL portal: publications by the organization WEBSITE

The QualiSud unit develops scientific activities aimed at analyzing, understanding, and optimizing the process of building food quality throughout the processing chain. Sensory quality, health effects, and health risks are given particular attention. The research activities of the QualiSud joint research unit are structured around five scientific areas: bioguiding of processes based on the sensory qualities and health benefits of food; control of post-harvest quality of fresh fruit and vegetables; strategies for the prevention and control of mycotoxins throughout the food chain; study of transfers and reaction kinetics during the fermentation of solid foods; multi-criteria analysis and design for decision support in the agri-food industry. Label: Joint Research Unit Research UMR) Main supervisory bodies: UM, CIRAD, IRD, Institut Agro, U RÉUNION, UAPV Research cluster: Agriculture, Environment, Biodiversity – AEB Doctoral school: Biodiversity, Agriculture, Food, Environment, Earth, Water HAL portal: publications by the organization WEBSITE

Numerous interactions take place between the various micro- and macro-organisms in agro-ecosystems and plants. These interactions, which determine plant health, growth, and productivity, are often poorly understood. The PHIM joint research unit produces knowledge and solutions to improve plant health and increase their productivity and quality. PHIM uses approaches from molecular biology and genetics, population genetics and genomics, epidemiology, and population dynamics and modeling to study these interactions at scales ranging from the cell to the cultivated plant plot. Label: Joint Research Unit Research UMR) Main supervisory bodies: CIRAD, INRAE, IRD, Institut Agro Secondary supervisory body: UMP Research cluster: Agriculture, Environment, Biodiversity – AEB Doctoral school: Biodiversity, Agriculture, Food, Environment, Earth, Water HAL portal: publications by the organization WEBSITE

OREME focuses its scientific activities on natural hazards and the impact of global and anthropogenic changes on the Mediterranean region, drawing on the scientific and technical expertise of its partners in geosciences, hydrosciences, biodiversity sciences, and ecology. Its mission is to: support systematic observation in space and environmental science; to support the construction of open, shared, internationally referenced environmental databases; to encourage the pooling of analytical resources (observation, experimentation, modeling) and expertise; to act as the local relay for national observation networks and position itself as a key player in environmental actions focused on the Mediterranean. OREME is therefore interested in three fundamental questions: the origin and assessment of natural and anthropogenic hazards and disturbances; the recording of recent and current global changes, their links with anthropogenic factors, and in particular changes in the use of Mediterranean environments; the response of the systems and mechanisms involved. Drawing on the training resources of the University of Montpellier for its educational mission, OREME focuses on its ability to mobilize heavy and sustainable observation resources and recognized scientific and technical expertise on a wide range of aspects of the physical, chemical, and biological environment of the Mediterranean: geodesy, gravimetry, and deformation of the Earth and its surface; hydrogeological, hydric, and geophysical monitoring of aquifers, particularly karst aquifers; monitoring of the Languedoc coastline, the interface between the watershed and the marine environment, and the coastline; pollution and biological adaptability downstream of former mining sites; flow measurements (CO2, water, gas) and ecosystem functioning; phenology of terrestrial flora and fauna; dynamics of animal and plant communities; dynamics of model organism populations. It also houses three major regional technical platforms: GLADYS for integrated coastal studies, AETE for water pollution analysis, and the Sète Marine Station (SMEL). OREME's permanent observation enables the collection and dissemination of data on environmental change at the national and international levels, as well as the conduct of fundamental and applied research. Label: Support and Research Unit Research UAR) Main supervisory bodies: CNRS, UM, INRAE, IRDP Research cluster: Agriculture, Environment, Biodiversity – AEB HAL portal: publications by the organization WEBSITE

MIVEGEC conducts integrative research on the molecular and ecological mechanisms that maintain and/or amplify the persistence and transmission of pathogens. The topics cover a broad spectrum, combining fundamental aspects of biology, genetics, ecology, and evolution of parasitic and symbiotic systems with more specific objectives of developing tools and strategies to reduce the spread of diseases in humans and animals, particularly through integrated ecosystem management and insect vector control. This places MIVEGEC at the interface between public health and the environment, biology and medicine, ecology and evolution. This research applies to various infectious models (parasites, viruses, bacteria, etc.) as well as to models that are not strictly infectious, such as cancer. Label: Joint Research Unit Research (UMR) Main supervisory bodies: CNRS, UM, IRD Secondary supervisory body: INRA Research cluster: Agriculture, Environment, Biodiversity – AEBE Doctoral schools: Chemical and Biological Sciences for Health; Biodiversity, Agriculture, Food, Environment, Earth, Water HAL portal: publications by the organization WEBSITE

https://youtu.be/RvoapzUL1wc L’objectif général de l’UMR concerne l’étude de la biodiversité marine des écosystèmes lagunaires, côtiers et hauturiers à différents niveaux d’intégration (moléculaire, individu, population et communauté), et des usages de cette biodiversité par l’Homme. S’appuyant sur des outils variés d’observation, d’expérimentation, d’analyse et de modélisation, l’unité répond plus spécifiquement aux objectifs suivants : décrire la biodiversité marine, comprendre sa dynamique et le fonctionnement des écosystèmes marins ; analyser l’impact des pressions anthropiques sur ces écosystèmes et développer des scenarii de réponses au changement global ; concilier exploitation (en particulier pêche et aquaculture) et conservation et répondre aux attentes sociétales (expertise, innovation, remédiation). Label : Unité Mixte de Recherche (UMR)Tutelles principales : UM, IRD, CNRS, IFREMERPôle de recherche : Agriculture, Environnement, Biodiversité – AEBÉcole doctorale : Biodiversité, Agriculture, Alimentation, Environnement, Terre, EauPortail HAL : publications de la structure SITE WEB

Research at ISEM focuses on the origin and dynamics of biodiversity, as well as the modalities and mechanisms of its evolution. Researchers at this unit are interested in both current and past biodiversity, studying a wide range of organisms and environments and combining field, experimental, and theoretical approaches. This research incorporates: fundamental questions of evolutionary biology (adaptation, constraints, speciation, etc.) to understand the mechanisms underlying biodiversity, its structure, and its functioning; the acceleration of data production methods and the ability to understand the different structural and functional dimensions of living organisms (from genes to ecosystems), leading to a comprehensive understanding of the mechanisms underlying biodiversity; Scientific and societal questions concerning the responses of biodiversity (organisms and/or communities) to global and anthropogenic changes. Label: Joint Research Unit Research UMR)Main supervisory bodies: CNRS, UM, IRD Secondary supervisory bodies: CIRAD, EPHE Research cluster: Agriculture, Environment, Biodiversity – AEBE Doctoral schools: Information, Structures, Systems; Chemical and Biological Sciences for Health; Biodiversity, Agriculture, Food, Environment, Earth, Water HAL portal: publications by the structure WEBSITE

The IPSIM joint research unit seeks to elucidate the physiological mechanisms that govern plant water and mineral nutrition and their responses to abiotic stresses and climate change (water stress, salt stress, mineral deficiencies, metal toxicity, CO2, high temperatures). The programs focus on water and mineral ion transport in plants, mineral accumulation in seeds, mechanisms of perception and signaling of environmental stresses, and developmental responses to these stresses (especially in the root system). The approach is that of integrative biology, which combines molecular and cellular biology, biochemistry and biophysics, functional genomics, and genetics approaches on model plants (Arabidopsis thaliana) or plants of agronomic interest (corn, rice, wheat, grapevine, lupin). Label: Joint Research Unit Research UMR) Main supervisory bodies: CNRS, UM, INRA Secondary supervisory body: Institut Agro Research pole: Agriculture, Environment, Biodiversity – AEB Doctoral school: Biodiversity, Agriculture, Food, Environment, Earth, Water HAL portal: publications by the structure WEBSITE