Institute of Human Genetics (IGH)
The IGH conducts cutting-edge basic research and aims to advance it to the point where it yields practical applications in the field of pathology. Its main research areas include genome and chromatin dynamics, developmental genetics, epigenetic regulation, and molecular and cellular pathologies.
Three major areas of research have been established within the IGH:
- Genome dynamics and epigenetic regulation. The main areas of this research include DNA replication, maintenance of genomic integrity, recombination and meiosis, retrotransposition and its regulation, chromatin and nuclear organization, regulation of gene expression, and RNA silencing.
- Developmental genetics. This research relies heavily on model organisms such as Drosophila and transgenic mice. Topics covered include the cell cycle and microtubule dynamics, gonadal development, RNA regulation in development, neurogenetics, and memory.
- The understanding, diagnosis, and treatment of human diseases. This research focuses on DNA metabolism, epigenetic regulation and signaling pathways in cancer, the molecular basis of myogenesis, immunity, inflammatory diseases, AIDS, neurodegenerative diseases, and cell therapies.
Affiliation:Joint Research Unit Research UMR)
Primary sponsoring organizations: CNRS, UM
Research cluster:Biology and Health
Doctoral school:Chemical and Biological Sciences for Health
HAL portal: publications from this unit
