Institute of Human Genetics (IGH)
The IGH conducts fundamental research of excellence and aims to apply its findings to the field of pathology. The main research topics concern genome and chromatin dynamics, developmental genetics, epigenetic control, and molecular and cellular pathologies.
Three major areas of research have been established within the IGH:
- Genome dynamics and epigenetic control. The main aspects of this research concern DNA replication, maintenance of genome integrity, recombination and meiosis, retrotransposition and its control, chromatin and nuclear organization, gene expression regulation, and RNA silencing.
- Developmental genetics. This research relies heavily on model organisms such as Drosophila and transgenic mice. Topics covered include the cell cycle and microtubule dynamics, gonad development, RNA regulation in development, neurogenetics, and memory.
- Understanding, diagnosing, and treating human diseases. This work focuses on DNA metabolism, epigenetic regulation and signaling pathways in cancer, the molecular basis of myogenesis, immunity, inflammatory diseases, AIDS, neurodegenerative diseases, and cell therapies.
Label:Joint Research Unit Research UMR)
Main supervisory bodies: CNRS, UM
Research cluster:Biology and Health
Doctoral school:Chemical and Biological Sciences for Health
HAL portal: publications by the organization
