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The “EuroMov Digital Health in Motion” research unit aims to foster cross-fertilization between artificial intelligence, movement sciences, and health to understand human behavioral plasticity in order to improve sensorimotor performance and explore new therapeutic approaches, and to find in this a scientific metaphor that serves as a source of inspiration for new digital approaches: machine learning or adaptive control of complex systems, human-machine interaction, and context-aware software systems. https://youtu.be/xaUOKgoUwYI?list=PL6WmOx60MnJe_iazdaxlxc1zC3Mx1K3Z0 This line of research on “Digital Health in Motion” ultimately aims to better understand the etiology of human movement—considered as the level of integration of biological and cognitive phenomena—during our constant exchange of information with the environment. The research unit is organized into three scientific themes and two cross-cutting areas: Perception In Action & Synchronization (PIAS) Theme: to uncover the laws governing human perception in moving agents (perception in action) and human-environment synchronization in general. Monitoring and Improving Behaviors (MIB) Theme: to provide users with guidance to improve their behaviors in order to achieve better health, quality of life, or athletic performance, with a particular focus on software engineering. The Learning and Complexity (LAC) theme focuses on the study of human learning and complexity through movement signatures related to health, clinical data, and indicators of neural activity, notably by developing interpretable models. Cross-cutting Theme: Semantics and Taxonomy of Movement (SemTaxM): to identify taxonomic classifications of movement and define a theory of movement-based semantics and semantic models grounded in specific contexts. The cross-cutting research area “Factory” aims to improve the reproducibility of results and accelerate translational research and technology transfer by providing standardized and documented approaches, along with a strategy for open data dissemination. Label: UR_UM102Primary Affiliations:UM, IMT Mines AlèsResearch Cluster: Biology and HealthDoctoral Schools: Information, Structures, Systems; Human Movement SciencesHAL Portal: publications by the unit WEBSITE

The DMEM Laboratory is a joint research unit of INRA and the University of Montpellier. We are interested in understanding the tissue, cellular, and molecular mechanisms that enable skeletal muscles to develop properly and adapt to their environment. Our hypothesis is that abnormalities in the adaptation of muscle tissue to environmental changes (diet, physical activity levels) can affect the body’s homeostasis and, more broadly, overall health. The DMEM is therefore a basic research unit whose goal is to advance our understanding of the function and physiology of skeletal muscles. We are also open to potential applications of our research, as evidenced by our partnership with private companies interested in our findings. Label: Joint Research Unit Research UMR)Primary Sponsors:UM, INRAEResearch Cluster: Biology and HealthDoctoral Schools: Human Movement Sciences; Chemical and Biological Sciences for HealthHAL Portal: unit publications WEBSITE

Label: Joint Research Unit Research UMR) Primary sponsoring organizations:UM, Inserm, UPS Toulouse Research cluster: Biology and Health Doctoral school: Chemical and Biological Sciences for Health HAL portal: the unit’s publications WEBSITE

The Montpellier Center for Cell Biology Research is a laboratory of the CNRS and the University of Montpellier. The CRBM is internationally recognized in the field of molecular and cellular biology. Its research aims to understand the mechanisms controlling cell division, morphology, and adhesion under normal and pathological conditions, with a particular focus on cytoskeletal dynamics, post-translational modifications, and the intracellular signaling mechanisms regulating these cellular activities. Designation: Joint Research Unit Research UMR)Primary sponsoring agencies: CNRS, UMPResearch cluster: Biology and HealthDoctoral school: Chemical and Biological Sciences for HealthHAL portal: the unit’s publications WEBSITE

https://youtu.be/U-4QGKRe4wY Le CEMIPAI est un laboratoire de services du CNRS et de l’université de Montpellier, ouvert aux équipes académiques et aux entreprises. Il s’organise autour de l’un des plus grands laboratoires de sécurité microbiologie de niveau L3 de France, permettant de travailler en atmosphère contrôlée sur les prélèvements biologiques infectieux et les agents biologiques de classe 3, comme le virus de l’immunodéficience humaine (VIH), les virus des hépatites ou les virus transmis par les moustiques (Chikungunya, Dengue, Zika), les bactéries pathogènes et les prions. Le CEMIPAI accueille les équipes, forme les chercheurs à la manipulation des agents infectieux et développe des tests en cultures cellulaires permettant de rechercher des molécules d’intérêt thérapeutique développées par les chercheurs du privé et du public. Des équipements de pointe en microscopie super résolue permet d’observer cellules infectées, virus et bactéries à des échelles nanométriques. Label : Unité d’Appui et de Recherche (UAR)Tutelles principales : CNRS, UMPôle de recherche : Biologie SantéPortail HAL : publications de la structure SITE WEB

The CBS’s overall objective is to conduct cutting-edge research in structural biology, biophysics, and bioengineering to identify and characterize the fundamental mechanisms of life and their regulation across different scales of time and space (from individual molecules to living tissues and organisms) using integrative approaches. We are particularly interested in understanding the molecular and physical determinants of these processes using state-of-the-art methodologies. We believe that achieving these objectives requires studying the structure and dynamics of supramolecular assemblies at different scales, as well as gaining a detailed understanding of their assembly and regulatory mechanisms. Furthermore, our ambition is to study these processes in more integrated contexts, such as living cells or model organisms. Whenever possible, we also apply this knowledge to develop new therapeutic strategies for human health and disease. Label: Joint Research Unit Research UMR)Main sponsoring agencies: CNRS, UM, InsermResearch cluster: Biology and HealthDoctoral schools: Information, Structures, Systems; Chemical and Biological Sciences for HealthHAL portal: unit publications WEBSITE

BioCampus Montpellier is a research consortium that brings together 12 high-level technology platforms. These platforms serve a scientific community of 2,000 Professors most Professors teams are affiliated with the AGRO, CeMEB, and EpiGenMed Labex programs. The UMS offers its services to researchers in these units as well as to industry partners with the goal of establishing new collaborative networks. Its platforms offer “open access” services, scientific and technical expertise, training in the form of technology workshops, and more. Thematic Areas: Bioinformatics, Structural Biology, Animal Breeding and Functional Exploration, Histology, Imaging, Small Animal Imaging, Molecular Combing, Recombinant Proteins, Genomics, Pharmacology, Proteomics, Vectorology. Designation: Support and Research Unit Research UAR)Main sponsoring agencies: CNRS, UM, InsermResearch cluster: Biology and HealthHAL portal: the unit’s publications WEBSITE

Our unit’s research focuses on biocommunication between the cardiovascular/renal axis and metabolic tissues within the complex pathophysiological context of metabolic syndrome. Our research aims to better characterize the pathophysiological mechanisms involved in the damage to various target tissues (cardiovascular and metabolic) during metabolic dysfunction, as well as the bio-communication pathways between these tissues. Through this integrative approach to chronic diseases, we hope to develop new therapeutic strategies aimed at preventing damage to cardiovascular and metabolic tissues and thereby reducing cardiovascular risk and metabolic dysfunction. Label: UR_UM101Primary Administrative Unit: UMPResearch Cluster: Biology and HealthDoctoral School: Chemical and Biological Sciences for HealthHAL Portal: publications from this unit WEBSITE

The mission of the Sciences for Oenology unit is to conduct general research in plant biology, microbiology, biochemistry, chemistry, and physical chemistry, with a primary focus on the viticulture and winemaking sector. Researchers in the unit focus primarily on topics related to: The integrative physiology of oenological yeasts and the control of alcoholic fermentation; Phenolic compounds (biosynthesis, reactivity, physicochemical interactions, properties, and utilization). Label: Joint Research Unit Research UMR)Main sponsoring organizations: UM, INRAE, Institut AgroResearch cluster: Agriculture-Environment-Biodiversity (AEB)Doctoral school: Biodiversity, Agriculture, Food, Environment, Land, WaterHAL portal: unit publications WEBSITE

The QualiSud unit conducts scientific research aimed at analyzing, understanding, and optimizing the process of building food quality throughout the processing chain. Particular attention is given to sensory quality, health effects, and health risks. The research activities of the QualiSud Joint Research Unit (UMR) are structured around five scientific areas: process bioguidance based on sensory qualities and food safety; control of post-harvest quality in fresh fruits and vegetables; strategies for the prevention and control of mycotoxins throughout the food supply chain; study of mass transfer and reaction kinetics during the fermentation of solid foods; multicriteria analysis and design to support decision-making in the agri-food sector. Label: Joint Research Unit Research UMR)Main sponsoring organizations:UM, CIRAD, IRD, Institut Agro, U RÉUNION, UAPVResearch cluster: Agriculture, Environment, Biodiversity – AEBDoctoral school: Biodiversity, Agriculture, Food, Environment, Land, WaterHAL portal: the unit’s publications WEBSITE

Numerous interactions occur between the various micro- and macro-organisms in agroecosystems and plants. These interactions, which determine plant health, growth, and productivity, are often poorly understood. The PHIM Joint Research Unit (UMR) generates knowledge and solutions to improve plant health and increase plant productivity and quality. PHIM uses approaches from molecular biology and genetics, population genetics and genomics, epidemiology, and population dynamics and modeling to study these interactions at scales ranging from the cellular level to the crop plot. Label: Joint Research Unit Research UMR)Primary sponsoring institutions: CIRAD, INRAE, IRD, Institut AgroSecondary sponsoring institution: UMResearch cluster: Agriculture, Environment, Biodiversity – AEBDoctoral school: Biodiversity, Agriculture, Food, Environment, Earth, WaterHAL portal: the unit’s publications WEBSITE

OREME focuses its scientific activities on natural hazards and the impact of global and anthropogenic changes on the Mediterranean region, drawing on the scientific and technical expertise of its partners in geosciences, hydrosciences, biodiversity sciences, and ecology. Its mission is: to support the implementation or development of systematic observation in space and environmental sciences; to support the creation of open, shared, and internationally referenced environmental databases; to encourage the pooling of analytical resources (observation, experimentation, modeling) and expertise; to serve as the local hub for national observation networks and to position itself as a key player in Mediterranean-focused environmental initiatives. OREME therefore focuses on three fundamental questions: the origin and assessment of natural and anthropogenic hazards and disturbances; the documentation of recent and ongoing global changes, their links to anthropogenic factors, and in particular changes in the use of Mediterranean environments; the response of the systems and mechanisms involved. Drawing on the educational resources of the University of Montpellier for its educational mission, OREME focuses on its ability to mobilize extensive and sustainable observation resources, as well as recognized scientific and technical expertise, on a wide range of aspects of the Mediterranean’s physical, chemical, and biological environment: geodesy, gravimetry, and deformation of the Earth and its surface; hydrogeological, hydrological, and geophysical monitoring of aquifers, particularly karst aquifers; monitoring of the Languedoc coastline, the interface between watersheds and marine environments, and the shoreline; pollution and biological adaptability downstream of former mining sites; measurements of fluxes (CO₂, water, gases) and ecosystem functioning; phenology of terrestrial flora and fauna; dynamics of animal and plant communities; population dynamics of model organisms. It also houses three major regional technical platforms: GLADYS for integrated coastal studies, AETE for water pollution analysis, and the Sète Marine Station (SMEL). OREME’s continuous monitoring enables the collection and dissemination of data on environmental change at the national and international levels, as well as the conduct of basic and applied research. Designation: Support and Research Unit Research UAR)Primary sponsoring agencies: CNRS, UM, INRAE, IRDResearch cluster: Agriculture, Environment, Biodiversity – AEBHAL portal: the unit’s publications WEBSITE

MIVEGEC conducts integrative research on the molecular and ecological mechanisms that sustain and/or amplify the persistence and transmission of pathogens. The research topics cover a broad spectrum, combining fundamental aspects of biology, genetics, ecology, and the evolution of parasitic and symbiotic systems with more applied objectives aimed at developing tools and strategies capable of reducing the spread of diseases in humans and animals, particularly through integrated ecosystem management and the control of insect vectors. This places MIVEGEC at the intersection of Public Health and the Environment, Biology and Medicine, Ecology and Evolution. This research applies to various infectious models (parasites, viruses, bacteria, etc.) as well as to non-strictly infectious models such as cancer. Label: Joint Research Unit Research (UMR)Primary sponsoring agencies: CNRS, UM, IRDSecondary sponsoring agency: INRAEResearch cluster: Agriculture, Environment, Biodiversity – AEBDoctoral schools: Chemical and Biological Sciences for Health; Biodiversity, Agriculture, Food, Environment, Earth, WaterHAL portal: the unit’s publications WEBSITE

https://youtu.be/RvoapzUL1wc L’objectif général de l’UMR concerne l’étude de la biodiversité marine des écosystèmes lagunaires, côtiers et hauturiers à différents niveaux d’intégration (moléculaire, individu, population et communauté), et des usages de cette biodiversité par l’Homme. S’appuyant sur des outils variés d’observation, d’expérimentation, d’analyse et de modélisation, l’unité répond plus spécifiquement aux objectifs suivants : décrire la biodiversité marine, comprendre sa dynamique et le fonctionnement des écosystèmes marins ; analyser l’impact des pressions anthropiques sur ces écosystèmes et développer des scenarii de réponses au changement global ; concilier exploitation (en particulier pêche et aquaculture) et conservation et répondre aux attentes sociétales (expertise, innovation, remédiation). Label : Unité Mixte de Recherche (UMR)Tutelles principales : UM, IRD, CNRS, IFREMERPôle de recherche : Agriculture, Environnement, Biodiversité – AEBÉcole doctorale : Biodiversité, Agriculture, Alimentation, Environnement, Terre, EauPortail HAL : publications de la structure SITE WEB

Research at ISEM focuses on the origin and dynamics of biodiversity, as well as the processes and mechanisms underlying its evolution. Researchers in this unit study both current and past biodiversity, examine a wide range of organisms and environments, and combine field, experimental, and theoretical approaches. This research incorporates: fundamental questions in evolutionary biology (adaptation, constraints, speciation, etc.) to understand the mechanisms underlying biodiversity, its structure, and its functioning; the rapid advancement in data-generation methods and the ability to grasp the various structural and functional dimensions of life (from the gene to the ecosystem), leading to a comprehensive understanding of the mechanisms underlying biodiversity; scientific and societal inquiries into how biodiversity (organisms and/or communities) responds to global and anthropogenic changes. Affiliation: Joint Research Unit Research UMR)Primary sponsoring agencies: CNRS, UM, IRD; Secondary sponsoring agencies: CIRAD, EPHE; Research cluster: Agriculture, Environment, Biodiversity – AEB; Doctoral schools: Information, Structures, Systems; Chemical and Biological Sciences for Health; Biodiversity, Agriculture, Food, Environment, Earth, Water; HAL portal: the unit’s publications; WEBSITE

The IPSIM Joint Research Unit seeks to elucidate the physiological mechanisms that govern water and mineral nutrition in plants and their responses to abiotic stresses and climate change (water stress, salinity stress, mineral deficiencies, metal toxicity, CO₂, and high temperatures). Research programs focus on water and mineral ion transport in plants, mineral accumulation in seeds, the mechanisms of perception and signaling of environmental stresses, and developmental responses to these stresses (particularly in the root system). The approach is that of integrative biology, which combines methods from molecular and cellular biology, biochemistry and biophysics, functional genomics, and genetics, using model plants (Arabidopsis thaliana) or crops of agronomic interest (maize, rice, wheat, grapevine, lupin). Label: Joint Research Unit Research UMR)Primary sponsoring agencies: CNRS, UM, INRASecondary sponsoring agency: Institut AgroResearch cluster: Agriculture, Environment, Biodiversity – AEBDoctoral school: Biodiversity, Agriculture, Food, Environment, Earth, WaterHAL portal: the unit’s publications WEBSITE